Psoriasis is a systemic disease with many associated comorbidities. An association between renal diseases and psoriasis is known in adult patients, but little is known about this association in pediatric patients. Thus a recent study determined whether there exists an association between psoriasis and renal comorbidities in adult and pediatric patients. 

This cross-sectional study investigated the database of the largest healthcare maintenance organization in Israel and compared 68,836 psoriatic patients and 68,836 controls concerning renal comorbidities. 

The results were as follows:

• In adults, an inverse association was seen between psoriasis and dialysis and kidney transplantation, a positive association with other kidney diseases, and no association between psoriasis and chronic kidney disease.
• In comparing 9,127 pediatric patients with 9,478 controls, no association was observed between psoriasis and renal comorbidities, chronic kidney disease, dialysis, kidney transplantation, or other kidney diseases, even after adjusting for putative confounders. 

Thus, unlike adult patients, pediatric patients with psoriasis were not found to be at risk of kidney diseases.

Source: Friedland R, Kridin K, Cohen AD, et al. Psoriasis and renal disorders: a large-scale population-based study in children and adults. Dermatology. 2022. doi: 10.1159/000522228